Statistics of Primera División Uruguaya in season 1961.
It was contested by 10 teams, and Peñarol won the championship.
| Pos | Club | P | W | D | L | GF | GA | Pts |
| 1 | Peñarol | 18 | 13 | 4 | 1 | 51 | 22 | 30 |
| 2 | Nacional | 18 | 13 | 1 | 4 | 39 | 16 | 27 |
| 3 | Defensor | 18 | 9 | 5 | 4 | 35 | 27 | 23 |
| 4 | Danubio | 18 | 6 | 5 | 7 | 25 | 31 | 17 |
| 5 | Cerro | 18 | 3 | 10 | 5 | 24 | 26 | 16 |
| 6 | Racing Montevideo | 18 | 5 | 5 | 8 | 30 | 45 | 15 |
| 7 | Rampla Juniors | 18 | 6 | 3 | 9 | 25 | 28 | 15 |
| 8 | Liverpool | 18 | 3 | 8 | 7 | 23 | 30 | 14 |
| 9 | Montevideo Wanderers | 18 | 3 | 6 | 9 | 23 | 35 | 12 |
| 10 | Fénix | 18 | 3 | 5 | 10 | 26 | 41 | 11 |
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